• MACRO Workstream 1
  • MACRO Worstream 1
  • MACRO Workstream 1
  • MACRO Workstream 1

The aim of the first section of research within the MACRO programme was to explore the current care pathways experienced by adults with Chronic Rhinosinusitis (CRS) within the NHS. 

This work was conducted in three parts;

  • The health informatics team analysed information routinely collected in the health records of patients with CRS to see which treatments they were receiving from GPs and hospital doctors and estimate how effective these were in terms of further healthcare visits and treatments. 
  • The health economics team analysed these pathways to establish how much they cost. 
  • The qualitative team interviewed patients and doctors to understand their attitudes towards the current treatment options offered within the NHS and also their views on the running of a clinical trial for adults with CRS. 

Taken together, this information allowed the MACRO researchers to understand how pathways of care differ between CRS patients with and without nasal polyps, how to optimise treatment of both groups of patients and design an appropriate clinical trial to further explore the best treatments (see workstream 2


Workstream 1 started in November 2016 and was completed at the end of 2017.

If you have any questions about the research within this Workstream, please contact the following researchers;